Healthy Life Extension
Who are the Smartest Patients? Here's the Surprising Answer
posted on January 29th, 2013
Dear Future Centenarian,
Right now one can't come to the hospital and say, "doctor, I've got a problem, I am aging."
Well you can, but you would be laughed out of the waiting room. However, this is the best kind of patient, the smartest one, one who cares about his or her future and wants to prevent upcoming illnesses and frailty. In other words¦ this is you.
Let's say you touched the light of truth and decide to convince people of the need to spend their resources on radical life extension. First, please accept my admiration. What you think is the most important task for you, for me and for all the people on the planet.
Now your goal is to convey a simple message to your buddies to live. The overwhelming majority stand against their own immediate death, but insist on the fact that the after-life is beautiful and that man should not argue with nature in the matter of aging.
There is another school in transhumanism, which states that people need to talk about a more moderate view of prevention of age-related diseases and healthy aging, and then most people will agree to help.
This agreement may be worth little, because for one, it has not yet gained any great success. But more importantly, it does not lead to scientific experiments aimed at radical life extension. I believe that you first need to attract people who want to live a long time, who want to live come what may. Then you deliver the motivation, a way to wake up such a person. You have the most wonderful news for him that ever he heard:
"You have a chance to age without aging!"
Here are some activists who are doing something about this now:
Research that could cure millions of chronic pain, disability and aging diseases
Many people believe stem cell therapy has great promise, but will not be available for 15 or 20 years. The reality is that adult stem cell therapy has already been utilized in a number of countries and in FDA trials with some success treating heart failure, MS, spinal cord injury, arthritis, joint problems and other conditions.
Unfortunately the current treatment does not work for everyone, and sometimes only barely. Much of the difficulty is that each of us only has a limited number of stem cells that can be used, and the greater their age, the less effective they are.
Centagen, Inc. has a new approach to expand your own stem cells up to a million times without aging. In fact, they may even be able to make your cells younger.
They believe this will greatly increase the success rate as well as improve results for those who have received only minimal benefits. This might even be a real beginning at reversing the aging process, since it supplies your body with a large number of your own rejuvenated stem cells to rebuild damaged and aged organs and tissues.
Even better, this type of adult stem cell therapy could be available soon.
This crowdfunding campaign ends January 31, and they are already starting operations on a shoestring. But you™re getting older every day, and they need support to make and keep you youthful.
Please help. Go to http://www.indiegogo.com/centagen now.
LATEST HEADLINES FROM FIGHT AGING!
BUT WHAT ABOUT PUSHKIN? Friday, January 25, 2013
From the Russian end of the longevity advocacy community: "A man strives for justice, but the most unjust thing in life is the inevitability of death.
Here's a small child, then an adult, he learns, grows up, falls in love, gets married - divorce, have children, he is happy and suffering, dreaming and disappointed, laughing and crying, running, resting, but for all that the fate is death, imminent death due to aging.
CONSIDERING CYBERNETIC IMMORTALITY Friday, January 25, 2013
If the 2045 initiative continues onwards as the founder intends, we're all going to be hearing more about what here is called "cybernetic immortality" - copying the data of the mind to run in machinery that is much more robust and longer-lasting than its biological equivalent.
I consider the popularity of this goal (as put forward by Ray Kurzweil, for example) something of an existential threat, insofar as it may drain enthusiasm and allies from work on rejuvenation biotechnology now, and in future decades it may become cheaper to build mind-copies than to finalize the means to reverse and prevent aging in our biological bodies.
ON LONG-LIVED CANCER-RESISTANT RODENTS Thursday, January 24, 2013
An open access review paper looks at the rise of mole-rats in cancer and aging research:
"Most rodents are small and short-lived, but several lineages have independently evolved long lifespans without a concomitant increase in body-mass.
LONGER TELOMERES, LESS CANCER IN CALORIE RESTRICTED MICE Thursday, January 24, 2013
Here's one of the hundreds of examples to show that the practice of calorie restriction improves near all measures of health and slows near all measures of aging:
"To carry out the study, researchers used young mice - just three months old - and reduced their caloric intake by 40% before observing them until the end of their life cycle. "We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet.
MORE ON CENTRAL CONTROL AND THE ACCEPTANCE OF DEATH Wednesday, January 23, 2013
Following on from yesterday's post on the pervasive acceptance of both aging to death and centralized control over society, here is another item that illustrates how state control of medical services and their funding via taxation distorts ethics in the matter of life and death.
It quickly becomes acceptable to talk about structuring countless deaths to reduce costs - the power of perverse incentives at work.
CONFIRMING THE IMPORTANCE OF AUTOPHAGY IN CALORIE RESTRICTION Wednesday, January 23, 2013
Autophagy is the collection of processes used by cells to remove and recycle damaged components and unwanted macromolecules.
More housekeeping is a better thing, and increased autophagy is linked to many of the genetic and metabolic alterations shown to extend life in laboratory animals. Here researchers confirm once more the importance of autophagy to the health and longevity benefits induced by calorie restriction:
SENS RESEARCH FOUNDATION: REIMAGINE AGING Tuesday, January 22, 2013
The SENS Research Foundation staff have launched their newly updated website:
"If this is your first time visiting our site, welcome. If you've been here before, you're no doubt noticing plenty that is new:
HEARING LOSS CORRELATES WITH COGNITIVE DECLINE Tuesday, January 22, 2013
Aging is a global phenomenon, occurring throughout the body, which is why correlations between the pace of different manifestations of degenerative aging are likely to happen and not necessarily linked by anything other than the fundamental causes of aging:
"[Researchers] studied 1,984 older adults (average age about 77 years) enrolled in a prospective observational study that began in 1997-1998.
SO HOW DO YOU MEASURE LIFE SPAN IN FLY STUDIES? Monday, January 21, 2013
The nuts and bolts of reliably measuring life span in small, numerous laboratory animals like flies and worms are glossed over in most of the materials presented here.
It's more complicated and prone to error than anyone would like it to be, and as for all such undertakings a whole field of knowledge and practice has been established over the years. Here's an interesting video presentation from the Journal of Visualized Experiments:
USING EPIGENETICS TO SEARCH FOR THE MECHANISMS OF RHEUMATOID ARTHRITIS Monday, January 21, 2013
Rheumatoid arthritis is a malfunction of the immune system, but like many autoimmune diseases, comparatively little progress has been made towards understanding its causes.
Here researchers are using epigenetic surveys to attempt to find genes of interest: " One probable factor involves chemical "tags" that attach to DNA sequences, part of a so-called epigenetic system that helps regulate when and how DNA sequences are "read," how they're used to create proteins and how they affect the onset or progress of disease.