35 Dynamic Years :)… then 35 in a Char :(

Healthy Life Extension

Funding Aging Research

35 Dynamic Years :)... then 35 in a Chair 🙁


Dear Future Centenarian,

Almost exactly half my lifetime ago, I got paralyzed from a freak spinal cord injury. I can't believe it's been 35 years since my last run.

I miss lots of other things that I can't do any more too.

From time-to-time, people ask me how it all feels. For a while, I was tempted to say: "It feels normal. "I got used to it." Well I'm here to tell you that after all this time, it doesn't feel normal, because it's not. Sure, I am used to it. People adjust to almost anything, even blindness and worse.

So it is with aging. You get used to it, but you miss your youth.

I'm not complaining about paraplegia or aging. What I am doing is trying to make an extremely important point.

What we gain, what advantages we are born with or are given... we tend to take for granted over time. But what we lose, we sorely miss.

Take money for example. Several times during my life, I made and lost what many would consider small fortunes. Making them was fun, even thrilling at times. But eventually the luster wore off and moderate wealth became a ho hum way of life.

But when I lost fortunes, it hit me like a hammer, and I still second guess myself.

How about you? Did you ever make an investment that went way up in value only to see it plunge back? I'll bet you mentally took possession of the money the investment represented (paper profits), and eventually took it for granted. But what happened when the value started eroding? What was your mental state when you lost, not half of your asset's value, but only half of your gains? Did you get emotional? Was it agonizing?

Did you ever want to kick yourself for not selling at the top or at least shortly after it started losing value? Did you hang on while desperately hoping it would go back up, only to see it fall further? Did you ever lose all or part of your original principal?

I'll bet your emotions ran a lot hotter during the loss periods than during the gains, right?

How about lost love? Or worse, a lost loved one? Or your favorite pet? Even though you valued them when you were together, I'll bet the agony of losing them was much more acute than the pleasure you derived from your relationships. We seldom completely get over big losses.

Here's a fact - People will go to the ends of the earth to recover what they lose... but barely make an effort to keep or improve what they have.

You know where I'm going with this, don't you? Your health.

Most people won't walk around the block and won't spend a dime for prevention, but they'll consume themselves in trying to cure what goes wrong. In my personal example, after a brief fling with suicidal thoughts, I chased this hope and that cure overseas for fifteen months before I finally realized I would have to support paralysis research here at home if I wanted to walk again. Of course I since "graduated" to a "higher calling"... helping the mission to reverse aging.

BTW, when I got hurt, I was incredibly fit, had an amazing business and lived in what was arguably the best place in the world for me. And I took it all for granted.

If you think about it, the best form of cure is prevention. It's less painful, much cheaper, and it works so much better.

Here at Maximum Life Foundation, we aim to cure aging. The way to do that in the intermediate term is the SENS approach, which is to repair the damage that aging does to you.

Another practical and immediately available option is to position yourself for the ultimate cure by buying yourself more time now. Simply adopt the seven strategies I illustrate in Smart, Strong and Sexy at 100. That could potentially add up to 25 active years to your life. IMO... a no brainer approach.

Let's face it, if you're a baby boomer or older, you're probably not going to make it unless you take action. No magical fairy is going to come to your rescue. Passively waiting for a cure as you age simply won't cut it. If you want the possibility of open-ended youthfulness, you'll need to be proactive. Are you up to the challenge?

Please, please, please take care of yourself!

Don't get complacent if you're younger than boomers either. If you were born later than 1964, you have a much better chance, but still only a chance. All the more reason to get to work on yourself NOW! Many in your generation will be part of the last group to die from aging.

Miss this plane and there's no next flight.

Let's take a peek at where that plane will take you - not only should you recapture your youth, but you will certainly be BETTER than before in numerous ways.

You'll look young and you won't age. You'll be smarter, stronger, disease and injury resistant, better looking and more. And then guess what will happen over time? Yep, you'll take all these enhancements for granted because you'll still be human.

Now I'm going to go out and celebrate all the good things in life, reflect over my last 35 years and plan my next 35.

More Life,
David Kekich


Latest Headlines from Fight Aging!

Rapamycin Partially Reverses Accelerated Degeneration in OXYS Rats - Monday, July 1, 2013
OXYS rats are a laboratory breed engineered to show accelerated aging. They exhibit higher levels of oxidative free radicals than other rats, and degenerate more rapidly.

Here researchers show that rapamycin, demonstrated to extend life in mice in recent years, can partially reverse accelerated degeneration in OXYS rats. Rapamycin is
already an FDA-approved drug as for its merits as a basis for treatments.

Read More http://www.fightaging.org/archives/2013/07/rapamycin-partially-reverses-accelerated-degeneration-in-oxys-rats.php

NF-?B Pathway Activators as Biomarkers and Targets for New Therapies in Aging - Monday, July 1, 2013

NF-?B shows up in a range of research on longevity and aging.

It's one of a number of central pieces of biological machinery that appear to be altered by methods of extending life in laboratory animals, but which influence (usually indirectly) so very many processes and mechanisms that understanding how it all fits together becomes an enormous task. In this open access paper researchers look at NF-?B in the context of the immune system failure and systematic chronic inflammation that occurs with aging.

Read More http://www.fightaging.org/archives/2013/07/nf-b-pathway-activators-as-biomarkers-and-targets-for-new-therapies-in-aging.php

Exploring Cryonics - Tuesday, July 2, 2013
Cryonics is the low-temperature preservation of the brain and body on death, so as to preserve the tissue structures that hold the data of the mind.

This offers a chance of future restoration to life via advanced medical technologies, which is more than can be said for the other post-mortem options presently available to us. Here is an interview with Max More of the Alcor Life Extension Foundation, one of the two long-established cryonics providers in the US.

Read More http://www.fightaging.org/archives/2013/07/exploring-cryonics.php

Radical Life Extension Conference, September, Washington DC - Tuesday, July 2, 2013
Supporters of radical life extension research are organizing a conference in Washington, DC, this coming September 22nd.

Read More http://www.fightaging.org/archives/2013/07/radical-life-extension-conference-september-washington-dc.php

Old Muscles Remain Surprisingly Capable of Regeneration - Wednesday, July 3, 2013
You might recall that in some ways muscle tissue shows a surprising lack of degeneration associated with aging. Not every measure and biological mechanism declines greatly.

It's not all that comforting, as evidently we're all still aging into frailty regardless, but it does suggest that perhaps a larger fraction of muscle aging than previously thought is under our control, the result of poor lifestyle choices such as sedentary behavior.

Read More http://www.fightaging.org/archives/2013/07/old-muscles-remain-surprisingly-capable-of-regeneration.php

A View of Current Options for Treating Osteoporosis - Wednesday, July 3, 2013

Bone weakens with age, a condition known as osteoporosis. Like many aspects of aging it appears that this can be partially slowed by means of calorie restriction, but prevention is going to require new medical technology.

Patching over the underlying causes, such as by interfering in the behavior of cells that create and destroy bone tissue, is the focus of the research mainstream. The better approach is to repair the underlying damage that causes aging, as detailed in the SENS proposals, and thereby eliminate the changes in our cell populations that cause bone to weaken.

Read More http://www.fightaging.org/archives/2013/07/a-view-of-current-options-for-treating-osteoporosis.php

How to Build a Heart via Decellularization - Thursday, July 4, 2013
Decellularization is the process of taking a donor organ and stripping its cells, leaving behind the extracellular matrix and all its chemical cues. The organ can then be repopulated with a patient's cells, producing working tissue for transplant that will not be rejected.

The donor organ doesn't even have to be human: decellularization greatly improves the prospects for xenotransplantation, such as obtaining hearts or kidneys from pigs. So far decellularization has only been used in human medicine for comparatively simple tissue structures, such as the trachea, but researchers are not very many years away from trials for decellularized hearts and other major organs.

Read More http://www.fightaging.org/archives/2013/07/how-to-build-a-heart-via-decellularization.php

News of Progress in Growing Liver Tissue from Stem Cells - Thursday, July 4, 2013
Last year Japanese scientists published on their work in growing small amounts of liver tissue from stem cells. Here is more on this line of research.

Read More http://www.fightaging.org/archives/2013/07/news-of-progress-in-growing-liver-tissue-from-stem-cells.php

Instructing Stem Cells to Reverse Osteoporosis - Friday, July 5, 2013

This study was mentioned in a recent review of treatment options currently under development for osteoporosis, the systematic loss of bone mass and strength with age.

Read More http://www.fightaging.org/archives/2013/07/instructing-stem-cells-to-reverse-osteoporosis.php

Towards Heart Regeneration With Pluripotent Stem Cells - Friday, July 5, 2013

As these authors note, progress towards heart regeneration via stem cell therapies is ongoing.

Numerous important steps forward in the control and manipulation of heart cells and stem cells have been demonstrated in the laboratory in recent years.

Read More http://www.fightaging.org/archives/2013/07/towards-heart-regeneration-with-pluripotent-stem-cells.php


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