Healthy Life Extension
posted on December 11th, 2012
Dear Future Centenarian,
Everyone needs a backup plan.
Sure, I know the œburn the boats story. But the boat in this case is your life and the goal is not conquering the Aztecs.
By dying prematurely, you will miss out on unimaginable wonders, wonders that we have a hard time conceiving today. But let™s try.
Imagine you could have EVERYTHING you want. You may have played this mind game at least once. I™ll bet a lot more times than that, huh?
Now let™s go way back in time. But before we do so, do you ever get bored? Now let™s go back, say thousands of years.
Unless you were part of a royal family or a tribal chieftain, one day in the average person™s lifetime today might be more interesting than the entire lifetime of boredom that most would have experienced then. Think about it. They woke up and looked for food. They ate and maybe stored what they found, killed or grew, and the day was basically over. Their entire existence was seeking subsistence. And they often died or were killed in the process.
In their wildest dreams, they could not have imagined the wonders that we take for granted today. They could no more understand the concepts of smartphones, airplanes and microwaved popcorn than we can predict what lies around the corner for us if we live to see it.
In prehistoric days, death may have been liberating. Today, it robs us of a cornucopia of unimaginable delights. It also robs us of mental and consciousness expansion. My friend, Kenton Mullins calls this an awesome privilege.
Doesn™t the prospect of witnessing future mysteries unfold fill you with curiosity and anticipation? If not, why not? Is it something that makes life miserable now? If so, the passage of time and future technologies will almost certainly make it a distant memory. Death is a long-term solution to short-term problems.
These are some of the reasons I dedicated my life to EXPANSION. More of everything that we treasure. And first and foremost¦ extreme life extension to make it possible for us to continue to grow.
So what™s your backup plan? Do you have one? I do, and I™ll reveal it to you next week.
LATEST HEADLINES FROM FIGHT AGING!
PGC-1 ALPHA-4 SPURS MUSCLE GROWTH Friday, DecemberÂ 7, 2012
Researchers have found a number of potential ways to spur growth of muscle tissue, and some of these might be used in attempts to fend off the loss of muscle mass and strength that occurs with aging - not by fixing the root causes, but by trying to compensate through another mechanism. Here is a recent example:
BEING OLDER IS VERY POSITIVE, BEING AGED IS NOT Friday, DecemberÂ 7, 2012
It should be noted that, on balance, everything except physical health becomes better with age.
Outside of degenerative aging, becoming older is so good that people are driven to apologism for the fact that aging cripples and kills them - they conflate being old and being aged, seeing two very different things as one, and a certain confusion arises after that point.
A BRIEF LOOK AT RETINAL IMPLANTS Thursday, DecemberÂ 6, 2012
Retinal implants are currently in their earliest stage of development: comparatively crude electrode arrays that provide an alternative to vision rather than restoring it.
From here the path to ever more sophisticated systems seems assured, however: "A coming generation of retinal implants that fit entirely inside the eye will use nanoscale electronic components to dramatically improve vision quality for the wearer, according to two research teams developing such devices.
STEM CELLS AND SCAFFOLDS TO REGROW THE CORNEA Thursday, DecemberÂ 6, 2012
One of a number of methods under development to regenerate or rebuild the cornea is outlined here: "Using a combination of techniques known as microstereolithography and electrospinning, the researchers are able to make a disc of biodegradable material which can be fixed over the cornea.
The disc is loaded with stem cells which then multiply, allowing the body to heal the eye naturally.
TRIALING REGENERATIVE MEDICINE FOR HEART FAILURE Wednesday, DecemberÂ 5, 2012
Since clinical trials for comparatively simple forms of stem cell therapy seem to be today's topic, here is another example:
"Cardio3 BioSciences (C3BS) announced it has received authorization from the Belgian Federal Agency for Medicines and Health Products (FAMHP) to begin its Congestive Heart failure Cardiopoietic Regenerative Therapy (CHART-1) European Phase III trial.
FIRST GENERATION STEM CELL THERAPIES MOVING THROUGH TRIALS Wednesday, DecemberÂ 5, 2012
Stem cell therapies based on comparatively uncomplicated transplants of cells - either grown from the patient's own tissue or from donors - are still working their way through trials in the more regulated parts of the world, and will be for years yet.
For wider access to these therapies, one has to look to medical tourism and reputable clinics overseas.
DIASTOLIC DYSFUNCTION CORRELATES WITH AGE LEVELS Tuesday, DecemberÂ 4, 2012
Advanced glycation end-products (AGEs) are a form of metabolic byproduct that build up with age, causing increasing damage through their effects on cellular machinery, which ultimately manifest in harmful conditions such as reduced elasticity in blood vessels and skin.
Ways to safely break down the most important forms of AGE would be greatly beneficial - but research aimed at achieving that goal is unfortunately very sparse and poorly funded.
AN INTERVIEW WITH A KRIORUS DIRECTOR Tuesday, DecemberÂ 4, 2012
Igor Artyukhov of the Institute of Biology of Aging is director of research for Russian cryonics provider KrioRus, and here is interviewed by Pravda:
"Pravda: If you live forever, then you stop rushing somewhere. You can always take time because it would seem that you will always have time for everything, that you can do everything later. Igor Artyukhov: If you know you'll die anyway, you do not rush either.
CONSIDERING NF-ÎºB IN AGING Monday, DecemberÂ 3, 2012
Researcher have been examining the role of NF-ÎºB in accelerated aging conditions such as Hutchinson-Gilford Progeria Syndrome, and believe that the findings may also be relevant as a basis for therapies to slow the ordinary progression of degenerative aging:
"NF-ÎºB transcription factors respond to a large variety of external and internal stress signals, having essential roles in development and tissue
REVIEWING THE ONLINE HUMAN AGING GENOMICS RESOURCES Monday, DecemberÂ 3, 2012
Since online databases on aging research have been a recent topic, here is an open access paper that discusses a set of such databases:
"The Human Ageing Genomic Resources (HAGR) is a freely available online collection of research databases and tools for the biology and genetics of ageing. HAGR features now several databases with high-quality manually curated data: