Plan B (Part II)

Healthy Life Extension

Funding Aging Research

Plan B (Part II)


posted on December 18th, 2012

Dear Future Centenarian,

Everyone needs a backup plan.

Last week I promised you I™d send you my backup plan.

Our ultimate plan at Maximum Life Foundation is to preserve human life. Yours, ours”everybody's. In keeping with that mission, we continue to seek out all the latest ground-breaking research and provide that information to you.

What if we don't succeed in time for you, though? Or what if you get whacked by an accident, another trauma or get blindsided by a deadly infectious disease?

Far from a sure thing, but scientifically sound enough to work, is a medical rescue protocol called cryonics. If you're not familiar with cryonics, research has shown that dying is not an event as once thought. Rather, it™s a gradual process that starts after, not when, our hearts or brain waves stop.

Our cells die gradually, over time. Cryonics is the methodology that halts this dying process with low-temperature technologies, stemming from the field of cryobiology. Remember when people were pronounced dead as soon as their hearts stopped beating? Physicians of the future will rarely pronounce people dead and will only do so after all advanced rescue technologies fail.

If the cryonics rescue team of today reaches patients in time after legal death, they may be able to place them into suspended animation, until such time as cures for what "killed" them are developed, and when age reversal technologies are mature. At that time, they plan on fixing you and waking you up.

A long-shot? Maybe. Wacky? If you think so, consider this:

Cryonics depends largely on two technologies. One is cryobiology, a well-proven field that deals with ultra-low temperatures. In this case, that means storing human tissue at liquid nitrogen temperatures for future therapies. This has been routine for many years.

The other is neurobiology, again, a totally legitimate and non-controversial field.

So it follows that it is just as legitimate to store and recover the brain (where your memory resides) while most of the cells are still alive, as it is to store and recover any other tissue. So cryonics should work.

But your odds get even better.

Add another emerging and soon to be maturing tool”regenerative medicine. We're already growing replacement organs, and soon, they promise to be as good as, or even better than the originals. Again, a well-accepted field.

As these technologies are fine-tuned, they may be more than enough for resuscitating patients. But there's more.

Another technology that may be enormously helpful for even more perfect rescue from suspension is nanotechnology. There's already more work in this field than I can ever hope to keep up with. Full-blown nanomedicine may be developed in as little as nineteen years.

Finally, an ace in the hole is Artificial General Intelligence (AGI) as described in Chapter Four of Smart, Strong and Sexy at 100? If you read that carefully, you™ll see the link between AGI and the ability to make something like cryonics work.

Not only would it counteract most arguments against cryonics, but it should enable patients to be reanimated much sooner than almost anyone thinks possible. And don™t forget the Law of Accelerating Returns. Don™t you think having research tools a billion times more powerful in 25-30 years would make cryonics technologies enormously more viable, even without AGI? 

Cryonics is not the extreme measure as some people mistakenly believe. It is actually the most conservative approach you can take if you are on the brink of death.

Burial and cremation guarantee 100% cell death. Cryonics preserves your cells and gives you a chance to recover. You need to plan ahead though, just like with traditional life insurance. In fact, you might look at cryonics preparation as the purest form of life insurance. Insurance is something you hope you never need but are glad you have when you do need it”when it is no longer for sale.

For more information, contact Alcor Life Extension Foundation at www.Alcor.org, or call 877-462-5267. They™ll send you a free information kit.

More Life,
David Kekich

P.S. Special congratulations to Google! Ray Kurzweil announced he agreed to assume the role of Director of Engineering for Google, Inc.
____________________________

LATEST HEADLINES FROM FIGHT AGING!

A LOOK AT TISSUE ENGINEERING RESEARCH Friday, December 14, 2012
MIT news here looks at the present state of tissue engineering, with a focus on work that is taking place at their own institution: "In the 1970s and 1980s, tissue engineers began working on growing replacement organs for transplantation into patients.

While scientists are still targeting that goal, much of the tissue engineering research [is] also focused on creating tissue that can be used in the lab to model human disease and test potential new drugs.

Read More http://www.fightaging.org/archives/2012/12/a-look-at-tissue-engineering-research.php

A DECADE IN LIFE EXPECTANCY GAINED SINCE 1970 Friday, December 14, 2012
Previous estimates of ongoing gains in life expectancy at birth put it at around a fifth of a year every year.

Life expectancy at 60 rises at about half that pace - a tenth of what is needed for actuarial escape velocity.

Read More http://www.fightaging.org/archives/2012/12/a-decade-in-life-expectancy-gained-since-1970.php

EMBRYONIC VERSUS INDUCED PLURIPOTENT STEM CELLS Thursday, December 13, 2012
A review paper here looks over the biochemistry, similarities, and differences between embryonic stem cells and induced pluripotent stem cells, both of which are presently used in the development of new therapies, but the former is far more limited by regulation than the latter:

Read More http://www.fightaging.org/archives/2012/12/embryonic-versus-induced-pluripotent-stem-cells.php

THE GENETICS OF EXTREME LONGEVITY Thursday, December 13, 2012
An open access review of the New England Centenarian Study:

"The New England Centenarian Study (NECS) was founded in 1994 as a longitudinal study of centenarians to determine if centenarians could be a model of healthy human aging.

Read More http://www.fightaging.org/archives/2012/12/the-genetics-of-extreme-longevity.php

SEEKING CORRELATIONS BETWEEN FERTILITY AND LONGEVITY IN HUMANS Wednesday, December 12, 2012
The results from this paper suggests that efforts to find any correlation between fertility and longevity in humans will be challenging, as in most data sets it will be swamped by associations with wealth, use of medical technologies to control fertility, and so forth:

Read More http://www.fightaging.org/archives/2012/12/seeking-correlations-between-fertility-and-longevity-in-humans.php

ON TARGETING SENESCENT CELLS TO TREAT AGING Wednesday, December 12, 2012
Senescent cells accumulate with age, disrupting the tissues they are in, promoting inflammation, and undertaking a range of other bad behavior.

Their presence is one of the causes of degenerative aging, and thus targeting them for destruction or reversal of their senescent state is a priority in longevity science:

Read More http://www.fightaging.org/archives/2012/12/on-targeting-senescent-cells-to-treat-aging.php

β-HYDROXYBUTYRATE IN CALORIE RESTRICTION Tuesday, December 11, 2012
Here is one research result among the many generated by scientists investigating the biochemistry of calorie restriction, seeking after a greater understanding of how it improves health and extends life:

"[Researchers] examined the role of the compound β-hydroxybutyrate (βOHB), a so-called "ketone body" that is produced during a prolonged low-calorie or ketogenic diet.

Read More http://www.fightaging.org/archives/2012/12/-hydroxybutyrate-in-calorie-restriction.php

CHANGING THE BEHAVIOR OF OLD SKIN CELLS Tuesday, December 11, 2012
The visible signs of skin aging are reflected by a similar loss of elasticity and function in important tissues inside the body, driven by declining function in stem cells that support these tissues, a steep growth in the number of senescent cells that hamper maintenance of tissue integrity, the accumulation of AGEs - largely glucosepane - and the other mechanisms that cause aging.

Read More http://www.fightaging.org/archives/2012/12/changing-the-behavior-of-old-skin-cells.php

TARGETING CANCER STEM CELLS VIA DNA REPAIR MECHANISMS Monday, December 10, 2012
The next generation of cancer therapies will involve ways to target and destroy cancer cells with far greater precision than is possible through presently available treatments, leading to highly effective therapies with few side effects.

One branch of this research and development effort involves targeting cells by characteristic differences in surface chemistry, but there are many others.

Read More http://www.fightaging.org/archives/2012/12/targeting-cancer-stem-cells-via-dna-repair-mechanisms.php

ENGINEERED T CELLS VERSUS LEUKEMIA Monday, December 10, 2012
The positive results of a cancer immunotherapy trial are noted here:

"Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients' tumors responded to the [therapy].

Read More http://www.fightaging.org/archives/2012/12/engineered-t-cells-versus-leukemia.php

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